Genetic Evidence Reveals Clues to Roots of Bipolar Disorder

Genetic Evidence Reveals Clues to Roots of Bipolar Disorder Bipolar disorder is a disorder characterized by periods of mania alternating with periods of depression, usually interspersed with relatively long intervals of normal mood (bipolar 2010). Bipolar can be a very debilitating psychological disorder, characterized by erratic and extreme changes in ones personality. An individual with bipolar may experience weeks or months of depression with alternating periods of mania, at which point the person may become hyperactive, irritable, restless and experience a rush thoughts and ideas. These â€Å"racing thoughts† are a common complaint of people with bipolar because it interferes with their ability to concentrate, speak, listen, complete†¦show more content†¦The association between Wnt and bipolar disorder has recently been supported by biological evidence that increasing the levels of GSk-3ÃŽ ² reverses the effects of lithium in the body. This is a direct explanation of how lithium and other drugs are effective in the treatme nt of bipolar patients. Family studies that Zandi and his research team have begun to conduct are beginning to look promising. His team has identified the response of a single nucleotide polymorphism (SNP), which was laying in the gene PPARD of a specific chromosome. After finding the first SNP, researchers were able to match its response to another SNP which had previously been identified as a bipolar cohort. Evertually they were able to locate four more associated with bipolar disorder, all of which were located on a single haplotype block, a combination of SNP’s, on gene PPARD. SNP’s are differences between DNA sequences that allow for genetic variations among humans. SNP’s are extremely difficult to identify, however new technologies have led to more recent discoveries. In the near future, as we gain more knowledge about them, SNP’s will allow researchers to revolutionize their ability to detect diseases, and develop preventative and curative medicine . Through his teams research they haveShow MoreRelatedOrganisational Theory230255 Words   |  922 Pages . viii Contents Chapter 2 Modernist organization theory: back to the future? Introduction Modernist organization theory in context What is modernism? Modernism and architecture What is modernist organization theory? The historical roots of modernist organization theory Classical theory of organization Modernist organization theory: an overview The modernist ontology: the ordered world of the modernist organization The epistemological level: the scientific approach to organizationRead MoreDeveloping Management Skills404131 Words   |  1617 PagesEmpowering and Delegating Effective Empowerment and Delegation 440 Personal Empowerment Assessment 441 SKILL LEARNING 443 Empowering and Delegating 443 A Management Dilemma Involving Empowerment The Dirty Dozen 444 The Meaning of Empowerment 445 Historical Roots of Empowerment 446 Dimensions of Empowerment 447 Self-Efficacy 447 Self-Determination 448 Personal Consequence 449 Meaning 449 Trust 450 Review of Empowerment Dimensions 451 How to Develop Empowerment 451 Articulating a Clear Vision and Goals 452 FosteringRea d MoreManagement Course: Mba−10 General Management215330 Words   |  862 Pagesor acceptable level of performance for a task, and then develop a pay system that provides a reward for performance above the acceptable level. To encourage workers to perform at a high level of efï ¬ ciency, and to provide them with an incentive to reveal the most efï ¬ cient techniques for performing a task, Taylor advocated that workers beneï ¬ t from any gains in performance. They should be paid a bonus and receive some percentage of the performance gains achieved through the more efï ¬ cient work process